Loneliness, immunological recovery patterns, and health-related quality of life (HRQOL) outcomes in patients receiving hematopoietic stem cell transplantation

Table 4 Associations of ANC/ALC ratio at Day 30 with FACT-BMT total score at Day 100 and 1 year

		Autologous transplant (N = 127)		Allogeneic transplant (N = 78)		All patients (N = 205)
Outcome	Association measure	Estimate (95% CI)	P-value	Estimate (95% CI)	P-value	Estimate (95% CI)	P-value
Association of ANC/ALC at day 30 with:
FACT-BMT total score
Day 100	Regression coefficient	-3.63 (-7.62, 0.37)	0.074	-7.33 (-12.13, -2.54)	0.004	-5.84 (-8.34, -3.33)	0.0001
1 year	Regression coefficient	-1.33 (-5.74, 3.09)	0.55	2.74 (-3.81, 9.28)	0.40	-0.87 (-3.92, 2.17)	0.57

CI = confidence interval. Regression coefficients, 95% CIs, and p-values result from linear regression models; regression coefficients are interpreted as the change in the mean FACT-BMT total score per each doubling in ANC/ALC (which was considered on the base 2 logarithm scale). Models were adjusted for age at transplant, sex, ethnicity, race, smoking history, current drinking, and BMI. Additionally, transplant subgroup was also adjusted for in analysis of all patients

ISSN: 2050-7283