Table 2 Association of clinicodemographic variables with QLQ-C30 and QLQ-H&N35 using GLM-MANOVA. GLM-MANOVA: General Linear Model Multivariate Analysis of Variance. * p value < 0.2 by one factor model of GLM-MANOVA. ** p value < 0.05 by multifactor model of GLM-MANOVA

Age (in years)

0.768 *

0.835 (< 0.001)**

Working status

0.805*

0.796 (< 0.001)**

Household Monthly Income (in PKR)

0.499*

0.555 (< 0.001)**

Hypertension

0.911*

NS

Diabetes Mellitus

0.915*

NS

Smokeless tobacco use

0.746*

0.783 (0.004)**

Family history of cancer

0.916*

NS

Types of tumor

0.798*

NS

Treatment of cancer

0.786*

NS

Types of Intervention

0.663*

0.71 (0.002)**

Feeding tube

0.73*

NS

Urine bag

0.841*

NS

Resilience

0.627*

0.824 (0.0001)**

Depression

0.459*

0.65 (< 0.001)**

Anxiety

0.649*

0.721 (< 0.001)**

Social support

0.854*

0.892 (0.041)**

EORTC QLQ H&N 35

Variables

One factor Model

Wilk λ (p value)

Multifactor Model

Wilk λ (p value)

Age (years)

0.851*

0.855 (0.0129)**

Gender

0.864*

0.825(0.0018)**

Monthly household income (PKR)

0.555*

0.599(0.003)**

Working status

0.831*

0.732 (< 0.001)**

Hypertension

0.886*

NS

Diabetes Mellitus

0.885*

NS

Smoking

0.772*

NS

Smokeless tobacco use

0.759*

NS

Family history of any other cancer

0.853*

NS

Types of tumor

0.682*

NS

Treatment of cancer

0.577*

NS

Types of Intervention

0.577*

NS

Adjuvant therapy

0.691*

0.678 (0.006)**

Urine bag

0.891*

NS

Resilience

0.562*

0.739 (< 0.001)**

Depression

0.739*

0.578 (< 0.001)**

Anxiety

0.482*

NS

Social support

0.775*

0.811(< 0.001)**