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Table 2 Measurements used in the study at the different assessment times

From: Development of a digital biomarker and intervention for subclinical depression: study protocol for a longitudinal waitlist control study

Measurement

Screening

T0

T1

T2

T3

Daily

Objective

Pregnant, Resp., Card., mental disease

X

–

–

–

–

–

–

Demographics

–

–

X

–

–

–

–

Distal outcomes

PHQ-9

X

X

X

X

X

–

2,3

GAD-7

X

X

X

X

X

–

2,3

TICS

–

X

X

X

X

–

2,3

Proximal outcomes

MDMQ1

–

–

–

–

–

X

1,3

Audio features

Voice commands

–

–

X2

X2

X2

X2

1,2

Breathing sounds

–

–

X2

X2

X2

X2

1,2

Conversational agent

Reaction time to chatbot messages

–

X

X

X

X

X

1,2

Therapeutic alliance

–

–

–

–

X

–

3

Qualitative feedback

Willingness continue using BEDDA

–

–

–

–

X

–

3

Willingness pay for BEDDA

–

–

–

–

X

–

3

Improvements suggestions

–

–

–

–

X

–

3

Breathing exercise Breeze

Location

–

–

–

–

–

X

3

Perceived breathing detection accuracy

–

–

–

–

–

X

3

Accelerometer

–

–

–

–

–

X2

1,2

Gyroscope

–

–

–

–

–

X2

1,2

Magnetometer

–

–

–

–

–

X2

1,2

Light sensor

–

–

–

–

–

X2

1,2

Ambient temperature sensor

–

–

–

–

–

X2

1,2

Humidity sensor

–

–

–

–

–

X2

1,2

Pressure sensor

–

–

–

–

–

X2

1,2

Step counts since start

–

–

–

–

–

X2

1,2

Proximity sensor

–

–

–

–

–

X2

1,2

Smartwatch groups

       

Physical activity

–

–

–

–

–

X3

1,2,3

Heart-rate

–

–

–

–

–

X3

1,2,3

Heart-rate variability

–

–

–

–

–

X3

1,2,3

Sleep duration, length of sleep phases

–

–

–

–

–

X3

1,2,3

Oxygen saturation

–

–

–

–

–

X3

1,2,3

Respiration rate

–

–

–

–

–

X3

1,2,3

Stress level

–

–

–

–

–

X3

1,2,3

Skin temperature

–

–

–

–

–

X3

1,2,3

Motion-based activity

–

–

–

–

–

X3

1,2,3

Steps

–

–

–

–

–

X3

1,2,3

  1. Intervention days are repeated measures collected over each day when completing the daily trip. 1Each day one of three dimensions (mood, agitation, anhedonia) is used. X2 Only while Breeze is used. X3 Only in the smartwatch group