Illness perceptions, fear of progression and health-related quality of life during acute treatment and follow-up care in paediatric cancer patients and their parents: a cross-sectional study

Herzog, Kristina; Schepper, Florian; Pletschko, Thomas; Herrmann, Jessy; Budich, Mihaela; Christiansen, Holger; Suttorp, Meinolf; Martini, Julia

doi:10.1186/s40359-023-01078-6

Table 4 Hierarchical multiple regression analysis for the outcome child’s HRQoL in follow-up care (n = 84)

From: Illness perceptions, fear of progression and health-related quality of life during acute treatment and follow-up care in paediatric cancer patients and their parents: a cross-sectional study

Predictor	B	SE B	t (p)	R^{2 †}	ΔR^{2 †}	F change (p)^†
Step 1: Sociodemographic and medical variables				.22	.22	4.406 (.001)
(Constant)	99.670	5.826	17.107 (< .001)
Child’s Age	− 1.432	0.446	− 3.208 (.001)
Diagnosis: lymphoma (dummy variable)^‡	− 2.958	4.416	− 0.670 (.503)
Diagnosis: tumour of the central nervous system (dummy variable)^‡	− 3.682	3.261	− 1.129 (.259)
Diagnosis: other solid tumour (dummy variable)^‡	− 1.865	3.603	− 0.518 (.605)
Time since diagnosis	− 0.056	0.034	− 1.684 (.092)
Step 2: Child’s illness perceptions				.28	.06	4.886 (< .001)
(Constant)	99.488	5.634	17.660 (< .001)
Child’s Age	− 0.889	0.484	− 1.838 (.066)
Diagnosis: lymphoma (dummy variable)^‡	− 1.890	4.290	− .440 (.660)
Diagnosis: tumour of the central nervous system (dummy variable)^‡	− 4.716	3.184	− 1.481 (.139)
Diagnosis: other solid tumour (dummy variable)^‡	− 1.684	3.485	− 0.483 (.629)
Time since diagnosis	− 0.066	0.033	− 2.004 (.045)
Child’s IPQ-R Symptoms	− 1.104	0.445	− 2.479 (.013)
Step 3: Child’s FoP				.35	.07	5.563 (< .001)
(Constant)	105.506	5.854	18.023 (< .001)
Child’s Age	− 0.787	.466	− 1.689 (.091)
Diagnosis: lymphoma (dummy variable)^‡	− 0.772	4.128	− 0.187 (.852)
Diagnosis: tumour of the central nervous system (dummy variable)^‡	− 3.211	3.097	− 1.037 (.300)
Diagnosis: other solid tumour (dummy variable)^‡	− 2.478	3.352	− 0.739 (.460)
Time since diagnosis	− 0.059	0.031	− 1.870 (.062)
Child’s IPQ-R Symptoms	− 0.875	0.438	− 1.999 (.046)
Child’s FoP	− 0.394	0.144	− 2.739 (.006)
Step 4: Parent’s illness perceptions				.42	.07	6.343 (< .001)
(Constant)	118.106	7.124	16.579 (< .001)
Child’s Age	− 0.966	0.448	− 2.155 (.031)
Diagnosis: lymphoma (dummy variable)^‡	− 2.293	3.975	− 0.577 (.564)
Diagnosis: tumour of the central nervous system (dummy variable)^‡	− 0.581	3.091	− 0.188 (.851)
Diagnosis: other solid tumour (dummy variable)^‡	− 2.686	3.205	− 0.838 (.402)
Time since diagnosis	− 0.040	0.031	− 1.296 (.195)
Child’s IPQ-R Symptoms	− 0.769	0.415	− 1.853 (.064)
Child’s FoP	− 0.361	0.140	− 2.585 (.010)
Parent’s IPQ-R Consequences	− 1.269	0.440	− 2.886 (.004)

^†R² and ΔR² were computed using the pooling technique suggested by van Ginkel [46]. F scores and p values were calculated using the miceadds-package from the statistics software R. Results from the original, non-imputed data set are comparable to those of the multiply imputed data set and are shown in the Additional file 6
^‡Reference category: Leukaemia

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ISSN: 2050-7283

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