|
Parameter
|
Arm A
|
Arm B
|
p value
|
|---|
|
(Male)
|
(Female)
|
|---|
|
(N = 229)
|
(N = 104)
|
|---|
|
n
|
%
|
n
|
%
|
|---|
|
Age, years
| | | | |
0.0010b
|
|
Mean (SD)
|
65 (8.8)
| |
62 (10.4)
| | |
|
Median (Q1, Q3)
|
66 (60, 72)
| |
61 (55, 69)
| | |
|
Range
|
36–84
| |
37–85
| | |
|
Comorbidities
| | | | |
0.2809b
|
|
Mean (SD)
|
3 (2.1)
| |
3 (2.1)
| | |
|
Median (Q1, Q3)
|
2 (1, 4)
| |
2 (1, 4)
| | |
|
Range
|
1–10
| |
1–10
| | |
|
ECOG
| | | | |
0.1643c
|
|
0
|
91
|
40
|
29
|
28
| |
|
1
|
107
|
47
|
60
|
58
| |
|
2
|
23
|
9
|
10
|
9
| |
|
3
|
2
|
1
|
1
|
1
| |
|
Missing
|
6
|
3
|
4
|
4
| |
|
Smoking habits
| | | | |
< 0.0001d
|
|
Smoker/ex-smoker
|
222
|
97
|
66
|
63
| |
|
Non-smoker
|
7
|
3
|
38
|
37
| |
|
Marital status
| | | | |
0.0002c
|
|
Single
|
25
|
11
|
19
|
18
| |
|
Married/Partnered
|
168
|
73
|
51
|
49
| |
|
Widowed
|
9
|
4
|
13
|
13
| |
|
Divorced
|
4
|
2
|
6
|
6
| |
|
Missing
|
23
|
10
|
15
|
14
| |
|
Educational level
| | | | |
0.0098c
|
|
No education
|
25
|
11
|
9
|
9
| |
|
Basic
|
118
|
52
|
37
|
35
| |
|
Higher
|
31
|
13
|
26
|
25
| |
|
Missing
|
55
|
24
|
32
|
31
| |
|
Histology
| | | | |
0.0082c
|
|
Adenocarcinoma
|
158
|
69
|
87
|
84
| |
|
Squamous cell
|
44
|
19
|
8
|
8
| |
|
Others
|
27
|
12
|
8
|
8
| |
|
Mutationsa
| | | | | |
|
EGFR+
|
11
|
5
|
21
|
20
| |
|
ALK+
|
4
|
2
|
5
|
5
| |
|
BRAF+
|
1
|
1
|
1
|
1
| |
- Italic values are statistically significant
- aEGFR mutation status was not determined in 67 men (29%) and 8 (8%) women; ALK mutation status was not determined in 103 men (45%) and 26 (25%) women; BRAF mutation status was not determined in 200 men (87%) and 93 (90%) women
- bWilcoxon signed-rank test
- cFisher’s exact test
- dChi-squared test
