Single-institution cross-sectional study to evaluate need for information and need for referral to psychooncology care in association with depression in brain tumor patients and their family caregivers

Reinert, Christiane; Gerken, Michael; Rathberger, Katharina; Krueger, Katharina; Klinkhammer-Schalke, Monika; Lindberg-Scharf, Patricia; Koelbl, Oliver; Proescholdt, Martin A.; Riemenschneider, Markus J.; Pukrop, Tobias; Bumes, Elisabeth; Hutterer, Markus; Hau, Peter

doi:10.1186/s40359-020-00460-y

Table 3 Results of univariable and multivariable binary logistic regression analysis on depression, yes vs. no according to PHQ-9 score (depression yes or no. 5+ vs. 0–4; N = 160, missings not shown; significant differences are shown in bold)

From: Single-institution cross-sectional study to evaluate need for information and need for referral to psychooncology care in association with depression in brain tumor patients and their family caregivers

		Univariable				Multivariable
		p-value	odds ratio	95% CI		p-value	odds ratio	95% CI
		p-value	odds ratio	lower	higher	p-value	odds ratio	lower	higher
Sex	Male		1.000				1.000
Sex	Female	0.787	1.091	0.580	2.051	0.963	1.028	0.316	3.347
Age	≤35		1.000				1.000
	36–50	0.298	1.647	0.643	4.218	0.089	3.530	0.824	15.129
	51–65	0.129	1.976	0.821	4.760	0.727	1.304	0.294	5.779
	> 65	0.649	1.273	0.451	3.590	0.163	0.181	0.016	2.003
Marital status	Single		1.000				1.000
Marital status	Partnership	0.843	1.077	0.518	2.238	0.571	1.446	0.404	5.175
Education level	Low		1.000				1.000
	Middle	0.873	0.925	0.359	2.389	0.801	1.214	0.269	5.473
	High	0.594	0.762	0.280	2.073	0.320	0.449	0.092	2.181
Working situation	Full time		1.000				1.000
	Part time	0.406	1.556	0.549	4.409	0.443	2.347	0.266	20.743
	Sick leave	0.128	2.750	0.748	10.105	0.096	4.717	0.759	29.298
	Retired	0.009	2.947	1.312	6.621	0.097	0.158	0.018	1.394
WHO grade	WHO I/II		1.000				1.000
	WHO III	0.881	1.059	0.499	2.247	0.620	0.724	0.201	2.601
	WHO IV	0.344	1.448	0.672	3.119	0.815	1.171	0.312	4.401
Tumor status	Primary diagnosis		1.000				1.000
Tumor status	Relapse	0.117	1.667	0.880	3.158	0.567	1.416	0.430	4.664
Time from diagnosis/relapse (years)	< 1.0		1.000				1.000
	1.0–4.9	0.465	0.750	0.346	1.624	0.584	1.494	0.355	6.289
	5.0+	0.754	1.168	0.442	3.086	0.109	3.759	0.745	18.977
	ns	0.315	0.594	0.215	1.639	0.887	1.123	0.226	5.586
Treatment status	Chemotherapy		1.000				1.000
	Radiotherapy/surgery	0.093	0.109	0.008	1.446	0.099	0.060	0.002	1.690
	Follow-up	0.132	0.447	0.157	1.275	0.115	0.238	0.040	1.418
	No treatment	0.006	0.193	0.059	0.628	0.344	0.394	0.057	2.715
Information level (diagnosis)	Informed		1.000				1.000
Information level (diagnosis)	Not informed	0.028	9.978	1.289	77.259	0.316	4.200	0.254	69.436
Information level (treatment)	Informed		1.000				1.000
Information level (treatment)	Not informed	0.040	3.775	1.063	13.405	0.756	1.416	0.158	12.666
Psychooncologic need	No (0–3)		1.000				1.000
Psychooncologic need	Yes (4+)	< 0.001	12.667	5.517	29.082	< 0.001	25.581	7.501	87.236

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ISSN: 2050-7283

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