Table 2 Effects of SGA on mean cognitive stores stratified by COMT rs5993883 genotype

Rey Visual Memory Immediate recall

20.9 (6.9)

17.4 (7.2)

−4.13

0.09

0.15

20.7 (6.7)

19.2 (6.4)

−1.8

0.88

0.22

22.2 (6.9)

20.0 (5.5)

−2.2

0.27

0.16

Rey Visual Memory Delayed recall

20.6 (6.9)

17.4 (7.4)

−3.96

0.11

0.14

21.0 (6.2)

19.3 (7.4)

−0.14

0.91

0.19

22.3 (6.8)

20.6 (6.1)

−2.25

0.25

0.23

CVLT-II^a learning score

56.6 (10.1)

45.1 (11.7)

10.88

0.0006

0.51

52.0 (12.2)

49.3 (10.9)

−1.77

0.46

0.17

55.2 (8.9)

50.1 (12.0)

−2.77

0.32

0.36

CVLT-II short term delayed free recall

11.6 (3.2)

9.8 (4.5)

−1.6

0.18

0.15

11.0 (3.4)

10.9 (3.5)

−0.12

0.85

0.15

12.0 (3.4)

11.1 (3.8)

−0.68

0.54

0.12

CVLT-II long-term delayed free recall

12.9 (3.1)

9.4 (3.2)

−3.43

0.0026

0.28

11.4 (3.7)

10.7 (3.1)

−0.22

0.75

0.18

12.7 (3.1)

11.0 (3.1)

−0.92

0.29

0.19

WCST^b total errors

24.4 (23.5)

27.5 (19.1)

9.3

0.21

0.21

25.1 (22.9)

23.7 (22.9)

−1.17

0.7

0.19

17.7 (15.9)

24.1 (24.2)

6.7

0.23

0.3

WCST perseverative responses

14.3 (15.4)

15.4 (14.6)

4.98

0.33

0.16

15.4 (16.3)

14.1 (16.4)

−1.61

0.62

0.18

9.5 (9.2)

14.5 (17.3)

5.27

0.17

0.25

WCST number of categories

5.2 (1.7)

5.2 (1.3)

−0.4

0.47

0.12

5.1 (1.7)

5.1 (1.9)

0.07

0.83

0.16

5.5 (1.4)

5.0 (1.9)

−0.52

26

0.28

TMT Part A Time (sec)

30.5 (13.3)

34.2 (10.9)

3.73

0.39

0.15

29.6 (9.9)

30.5 (11.9)

0.042

0.98

0.15

28.4 (9.3)

30.5 (11.5)

1.3

0.62

0.4

TMT Part B Time (sec)

75.9 (36.5)

82.1 (30.6)

2.44

0.83

0.16

72.5 (27.4)

80.6 (36.4)

3.5

0.55

0.25

65.2 (25.6)

80.5 (36.5)

10.6

0.2

0.35

PGNG^c response time (msec)

468.2 (47.2)

492.2 (61.6)

18.6

0.33

0.19

467.5 (53.4)

463.8 (59.5)

−1.79

0.55

0.2

451.2 (46.8)

459.6 (43.5)

11.3

0.38

0.22

PGNG Target accuracy (%)

0.96 (0.05)

0.88 (0.11)

0.083

0.004

0.23

0.95 (0.07)

0.95 (0.06)

0.002

0.86

0.17

0.98 (0.05)

0.96 (0.07)

−0.02

0.23

0.12