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Table 4 ACE decomposition of burden of social isolation (T1, T2)

From: Genetic and environmental contributions to the subjective burden of social isolation during the COVID-19 pandemic

 

T1: 2020

T2: 2021

 

Reduced model

Full model

Reduced model

Full model

Twin correlations

        

MZr

0.370

[0.236,0.505]

0.334

[0.197,0.471]

0.392

[0.317,0.466]

0.362

[0.286,0.437]

DZr

0.250

[0.120,0.380]

0.219

[0.082,0.357]

0.261

[0.191,0.331]

0.243

[0.170,0.315]

ACE decomposition (unstandardized variance components)

        

a2

0.348

[0.237,0.467]

0.321

[0.212,0.437]

0.366

[0.302,0.432]

0.355

[0.292,0.421]

c2

        

e2

0.603

[0.510,0.716]

0.597

[0.504,0.710]

0.575

[0.522,0.635]

0.575

[0.522,0.635]

Total variance (a2 + c2 + e2) (residual variance)

0.951

 

0.918

 

0.941

 

0.930

 

Variance explaineda

  

3.5%

   

1.2%

 

ACE decomposition (standardized variance components)

        

A

0.366

[0.256,0.465]

0.350

[0.237,0.452]

0.389

[0.327,0.446]

0.382

[0.320,0.440]

C

        

E

0.634

[0.535,0.744]

0.650

[0.548,0.763]

0.611

[0.554,0.673]

0.618

[0.560,0.680]

A + C + E

1.000

 

1.000

 

1.000

 

1.000

 

N

798

 

798

 

2520

 

2520

 

N twin pairs

399

 

399

 

1260

 

1260

 
  1. Source: TwinLife v6-0-0 CoV1 (T1), CoV2 (T2); Sample: cohorts 2, 3 & 4
  2. Reduced model adjusted for birth cohort and sex; 95% CI in brackets
  3. aThe proportion of variance explained by full model is calculated as follows: (variance reduced − variance full)/variance reduced