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Table 3 Hierarchical multiple regression analysis for the outcome child’s HRQoL in acute treatment (n = 46)†

From: Illness perceptions, fear of progression and health-related quality of life during acute treatment and follow-up care in paediatric cancer patients and their parents: a cross-sectional study

Predictor

B

SE B

β

t (p)

R2

ΔR2

F change (p)

Step 1: Sociodemographic and medical variables

    

.401

.401

5.363 (< .001)

(Constant)

79.134

5.046

 

15.682 (< .001)

   

Child’s Age

 − 1.292

0.443

 − .378

 − 2.916 (.006)

   

Diagnosis: lymphoma (dummy variable)‡

 − 2.451

5.013

 − .069

 − 0.489 (.628)

   

Diagnosis: tumour of the central nervous system (dummy variable)‡

2.006

4.809

.060

0.417 (.679)

   

Diagnosis: other solid tumour (dummy variable)‡

7.134

3.914

.267

1.823 (.076)

   

Time since diagnosis

0.297

0.095

.402

3.132 (.003)

   

Step 2: Child’s illness perceptions

    

.498

.097

3.643 (.036)

(Constant)

86.254

5.664

 

15.230 (< .001)

   

Child’s Age

 − 1.033

0.521

 − .302

 − 1.983 (.055)

   

Diagnosis: lymphoma (dummy variable)‡

 − 3.821

5.048

 − .108

 − 0.757 (.454)

   

Diagnosis: tumour of the central nervous system (dummy variable)‡

 − 1.810

4.735

 − .054

 − 0.382 (.704)

   

Diagnosis: other solid tumour (dummy variable)‡

5.486

3.819

.205

1.436 (.159)

   

Time since diagnosis

0.271

0.090

.366

3.012 (.005)

   

Child’s IPQ-R Symptoms

 − 0.203

0.624

 − .057

 − 0.325 (.747)

   

Child’s IPQ-R Timeline-cyclical

 − 4.563

1.953

 − .314

 − 2.336 (.025)

   

Step 3: Parent’s illness perceptions

    

.541

.044

1.718 (.194)

(Constant)

75.807

8.993

 

8.429 (< .001)

   

Child’s Age

 − 1.171

0.520

 − .342

 − 2.253 (.030)

   

Diagnosis: lymphoma (dummy variable)‡

 − 1.729

5.180

 − .049

 − 0.334 (.740)

   

Diagnosis: tumour of the central nervous system (dummy variable)‡

 − 1.616

4.651

 − .048

 − 0.348 (.730)

   

Diagnosis: other solid tumour (dummy variable)‡

5.650

3.830

.211

1.475 (.149)

   

Time since diagnosis

0.163

0.106

.220

1.540 (.132)

   

Child’s IPQ-R Symptoms

0.744

0.954

.209

0.781 (.440)

   

Child’s IPQ-R Timeline-cyclical

 − 5.381

1.978

 − .371

 − 2.721 (.010)

   

Parent’s IPQ-R Symptoms

 − 0.747

0.823

 − .200

 − 0.907 (.370)

   

Parent’s IPQ-R Timeline-acute/chronic

1.489

0.820

.273

1.816 (.078)

   
  1. †As no data of the variables included in the hierarchical multiple regression model was missing, the imputed model was the same as the original data set. Therefore, regression coefficients, determination coefficients and the F-statistics were the same across all m = 5 imputations and the original data set
  2. ‡Reference category: Leukaemia