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Table 1 Data summary

From: Depression in adults with sickle cell disease: a systematic review of the methodological issues in assessing prevalence of depression

Year Author Methodology Population Measure Results
Country Recruitment setting Sex (male, %) Age (mean) Genotype (SS, %) Type Name Cut-off N total % depressed
1999 Wilson Schaeffer, J. J et al USA Outpatient 43.86 33.70   PA CES-D 20 16 440 43.41
2000 Grant et al USA Outpatient 41.86 35.02   PA CES-D 20 16 43 25.58
2003 Hasan et al USA Outpatient 54.00 36.00 94.00 PA BDI-II 14 50 44.00
2005 Jenerette et al USA Cohort 28.00 35.00   PA BDI 7 4 221 31.67
2006 Laurence et al USA Cohort 43.54   79.40 PA CES-D 10 4 101 38.61
2007 Pells, J. et al USA Cohort   36.82   PA LEMFPSCD (BDI-II) 14 67 35.82
2008 Levenson et al USA Cohort 38.40 34.00 70.96 PA PHQ 9 10 232 27.59
2009 Carroll et al USA Inpatient 36.50 24.10   MRR   n/a 122 6.56
2009 Edwards et al USA Outpatient   36.82   PA LEMFPSCD (BDI-II) 14 67 22.00
2010 Anie et al Nigeria Outpatient     PA PISCD n/a 253 44.27
2010 Asnani et al Jamaica Cohort 49.46 31.00   PA BDI-II 14 277 21.66
2010 Kamble et al USA Outpatient 42.96 34.20   PA BDI-II 14 142 35.21
2010 Mahdi et al Bahrain Outpatient 42.80 17.23 100 PA DASS 21 10 243 59.26
2011 Carroll et al USA Inpatient     MRR   n/a 1874 4.27
2011 Treadwell et al USA Outpatient   31.20   PA PHQ 9 10 77 61.04
2012 Rosine Europe Outpatient 44.30 35.60 100 PA BDI-II 14 89 49.44
2012 Vilela et al Brazil Outpatient 32.00 35.00 100 PA BDI-II 20 24 16.67
2013 Gibson et al Jamaica Outpatient 48.00 36.40 70.00 PA BDI-II 17 143 13.29
2014 Morgan et al Jamaica Outpatient   35.97 69.60 PA BDI-II 14 140 15.00
2014 Wallen et al USA Cohort 49.00 34.00 85.00 PA BDI-II 16 315 20.63
2015 Mann-Jiles et al USA Outpatient 49.00   64.00 MRR   n/a 72 19.44
2015 Mastandréa et al Brazil Outpatient 38.20 30.00 72.70 PA PHQ 9 10 110 30.00
2015 Treadwell et al USA Cohort 40.00 31.60 73.00 PA PHQ 9 10 77 32.47
2016 Al Sherawi et al Oman Outpatient Inpatient 34.00    PA BDI-II 14 123 39.02
2016 Anim et al Ghana Outpatient 51.00   65.00 PA BSI ? 201 0.00
2016 Fayand et al Europe Inpatient 43.00 27.00   MRR   n/a 439 5.24
2016 Ola et al Nigeria Outpatient 38.83 25.30 98.06 PA PHQ 9 5 103 71.84
2016 Master et al USA Outpatient 48.00 33.00   PA PROMIS 55 100 35.00
2016 Raji et al Nigeria Outpatient 46.30 25.37   Interview Mini n/a 205 16.59
2017 Adam et al USA Outpatient 28.00 35.40 56.00 PA BDI-II 14 142 35.21
2017 Dorociak et al USA Outpatient 22.20 40.61   PA CES-D 20 16 54 38.89
2018 Alhomoud et al Saudi Arabia Outpatient 57.30 31.70 100 PA BDI-II 14 110 48.18
2018 Alsubaie et al Saudi Arabia Outpatient 35.90 26.40   PA HAM-D 17 8 78 85.90
2018 Ahmadi et al Iran Outpatient 35.10   64.90 PA DASS 21 5 97 67.01
2018 Williams et al USA Inpatient 52.00 27.50   Interview ED-Scan n/a 95 29.47
2018 Simo et al USA VOC 20.00   80.00 PA PHQ 9 10 10 50.00
  1. CES-D Centre for Epidemiologic Studies-Depression, BDI Beck Depression Inventory, LEMFPSCD Longitudinal Exploration of Medical and Psychosocial Factors in SCD, PHQ Patient Health Questionnaire, DASS Depression Anxiety Stress Scale, BSI Brief Symptom Inventory, Mini Mini International Neuropsychiatric Interview, PROMIS Patient-Reported Outcomes Measurement Information System, HAM-D Hamilton Depression scale
  2. (: estimated) (: SS + Sβ°) (VOC vaso-occlusive crisis, PA psychometric assessment, MRR medical record review, SI structured interview)