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Table 2 Sociodemographic and psychosocial parameters of Test Group and Observational Group at t0

From: Psychosocial impact of prognostic genetic testing in uveal melanoma patients: a controlled prospective clinical observational study

 

Test Group Total* n = 63 (36%)

Observational Group n = 112 (64%)

Statistical results

p

Age (M, SD, range)

57.68 (±12.03), 29–82

63.08 (±11.4), 37–84

U = 2604.50, z = −2.872

.004** a

Sex

   

.056b

 male

42 (66.7%)

58 (51.8%)

  

 female

21 (33.3%)

54 (48.2%)

  

Graduation

   

.196b

 Intermediate school or less (< 12 years)

40 (63.5%)

82 (73.2%)

  

 High School or higher

22 (34.9%)

29 (25.9%)

  

 No information

1 (1.6%)

1 (0.9%)

  

Treatment

  

χ2 = 34.666

<.001**d

 Enucleation

23 (36.51%)

8 (7.14%)

  

 Brachytherapy

25 (39.68%)

90 (80.36%)

  

 Endoresection with adjuvant brachytherapy

7 (11.11%)

3 (2.68%)

  

 Proton therapy

6 (9.52%)

7 (6.25%)

  

 Other

2 (3.17%)

4 (3.57%)

  

Resilience

70.08 (±11.16)

70.21 (±11.72)

 

.735a

Social Support

4.36 (±0.76)

4.51 (±0.54)

 

.499a

Fear of progression Total

2.34 (±0.72)

2.13 (±0.65)

 

.057a

 Affective reactions

2.65 (±0.79)

2.57 (±0.73)

 

.601c

 Partnership/Family

2.18 (±0.72)

2.02 (±0.66)

 

.134a

 Occupation

2.23 (±1.18)

1.77 (±1.02)

U = 2738.0, z = −2.510

.012**a

 Loss of autonomy

2.30 (±0.79)

2.17 (±0.85)

 

.202a

 Coping with anxiety

3.46 (±0.55)

3.63 (±0.55)

 

.058c

General Distress

6.15 (±2.53)

5.40 (±2.44)

U = 2874.0, z = −2.047

.041**a

Depression

5.10 (±3.76)

4.90 (±4.30)

 

.498a

Anxiety

7.62 (±4.15)

7.21 (±3.87)

 

.519c

Health-related quality of life

    

 Quality of life: Physical

49.93 (±7.74)

48.22 (±9.65)

 

.463a

 Quality of life: Mental

45.74 (±10.22)

44.57 (±11.82)

 

.682a

Perceived Risk

5.02 (±2.34)

4.06 (±2.31)

t(173) = 2.627

.009**c

  1. Note: Except as indicated, categorical data are presented as count (percentage), continuous data are presented as mean (±standard deviations), * Test Group Total = M3 (n = 31) + D3 (n = 27) + unclear biopsy (n = 5), ** p < .05, a = Mann-Whitney U-Test, b = Chi-Square Test, c = Independent t-Test, d = Fisher’s exact test