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Table 1 Characteristics of the cohort of 2355 post-myocardial infarction patients according to creatinine-cystatin C-based eGFR and serum CRP level

From: Kidney dysfunction, systemic inflammation and mental well-being in elderly post-myocardial infarction patients

 

Creatinine-Cystatin C-based eGFR, ml/min/1.73 m2

C-reactive protein levels, mg/L

≥60

(n = 1750)

<60

(n = 605)

P-value

<3

(n = 1564)

≥3

(n = 791)

P-value

Age, years

71.2 ± 5.04

75.4 ± 5.3

<0.001

72.0 ± 5.3

72.7 ± 5.6

0.004

Men, No. (%)

1465 (83.7%)

422 (69.8%)

<0.001

1291 (82.5%)

596 (75.3%)

<0.001

Higher education a, n (%)

767 (44.0%)

238 (39.7%)

0.064

715 (45.9%)

290 (36.9%)

<0.001

Body mass indexb, kg/m2

27.6 ± 3.6

28.1 ± 4.1

0.003

27.3 ± 3.4

28.6 ± 4.15

<0.001

Physically activec, n (%)

389 (22.3%)

87 (14.5%)

<0.001

340 (21.8%)

136 (17.3%)

0.010

Current smoker, n (%)

267 (15.3%)

83 (13.8%)

0.363

184 (11.8%)

166 (21.0%)

<0.001

Alcohol use ≥1 glass/week, n (%)

1286 (73.6%)

360 (59.9%)

<0.001

1135 (72.8%)

510 (64.8%)

<0.001

Antidepressant use, n (%)

78 (4.5%)

40 (6.6%)

0.036

67 (4.3%)

51 (6.4%)

0.023

Time since myocardial infarction, years

4.5 ± 3.1

4.7 ± 3.4

0.110

4.5 ± 3.2

4.7 ± 3.2

0.117

Self-reported history of stroke, n (%)

94 (5.4%)

58 (9.7%)

<0.001

84 (5.4%)

68 (8.7%)

0.003

Diabetesd, n (%)

93.1 (22.3%)

188 (31.1%)

<0.001

375 (24.0%)

204 (25.8%)

0.334

Systolic blood pressure, mmHg

142.9 ± 20.5

141.6 ± 23.7

0.188

143.4 ± 20.9

140.9 ± 22.1

0.006

Use of cardiovascular medicatione, n (%)

 Antithrombotic agents

1713 (97.9%)

584 (96.5%)

0.063

1529 (97.8%)

768 (97.1%)

0.322

 Blood pressure lowering drugs

1729 (98.8%)

591 (97.7%)

0.051

1537 (98.3%)

783 (99.0%)

0.176

 Statins

1553 (88.7%)

513 (84.8%)

0.011

1399 (89.5%)

667 (84.3%)

<0.001

High-sensitivity C-reactive protein, mg/L

1.42 (0.71-3.15)

3.33 (1.27-6.91)

<0.001

1.01 (0.61-1.72)

5.66 (4.04-8.83)

<0.001

Serum creatininef, mg/dl

0.96 ± 0.18

1.54 ± 0.61

<0.001

1.05 ± 0.33

1.22 ± 0.56

<0.001

Serum cystatin C, mg/L

0.89 ± 0.13

1.41 ± 0.42

<0.001

0.96 ± 0.24

1.15 ± 0.42

<0.001

  1. Data are presented as median (interquartile range), mean (± SD) or number (percentage of the total)
  2. aDefined as higher vocational education, college or university
  3. bBody mass index was calculated as weight in kilograms divided by height in meters squared
  4. cDefined as ≥3 Metabolic Equivalent Tasks (MET) during >5 days/week
  5. dDiabetes was considered to be present if a patient reported having received the diagnosis from a physician, was taking antidiabetic drugs, or had an elevated plasma glucose level (≥126 mg/dl in the case of patients who had fasted more than 4 h or ≥200 mg/dl in the case of non-fasting patients)
  6. eAntithrombotic agents ATC code B01. Blood pressure lowering drugs: ATC codes C02, C03, C07, C08 and C09. Statins: ATC code C10AA
  7. fTo convert the values for creatinine to μmol/L, multiply by 88.40
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BMC Psychology

ISSN: 2050-7283

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