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Table 1 Characteristics of the cohort of 2355 post-myocardial infarction patients according to creatinine-cystatin C-based eGFR and serum CRP level

From: Kidney dysfunction, systemic inflammation and mental well-being in elderly post-myocardial infarction patients

  Creatinine-Cystatin C-based eGFR, ml/min/1.73 m2 C-reactive protein levels, mg/L
≥60
(n = 1750)
<60
(n = 605)
P-value <3
(n = 1564)
≥3
(n = 791)
P-value
Age, years 71.2 ± 5.04 75.4 ± 5.3 <0.001 72.0 ± 5.3 72.7 ± 5.6 0.004
Men, No. (%) 1465 (83.7%) 422 (69.8%) <0.001 1291 (82.5%) 596 (75.3%) <0.001
Higher education a, n (%) 767 (44.0%) 238 (39.7%) 0.064 715 (45.9%) 290 (36.9%) <0.001
Body mass indexb, kg/m2 27.6 ± 3.6 28.1 ± 4.1 0.003 27.3 ± 3.4 28.6 ± 4.15 <0.001
Physically activec, n (%) 389 (22.3%) 87 (14.5%) <0.001 340 (21.8%) 136 (17.3%) 0.010
Current smoker, n (%) 267 (15.3%) 83 (13.8%) 0.363 184 (11.8%) 166 (21.0%) <0.001
Alcohol use ≥1 glass/week, n (%) 1286 (73.6%) 360 (59.9%) <0.001 1135 (72.8%) 510 (64.8%) <0.001
Antidepressant use, n (%) 78 (4.5%) 40 (6.6%) 0.036 67 (4.3%) 51 (6.4%) 0.023
Time since myocardial infarction, years 4.5 ± 3.1 4.7 ± 3.4 0.110 4.5 ± 3.2 4.7 ± 3.2 0.117
Self-reported history of stroke, n (%) 94 (5.4%) 58 (9.7%) <0.001 84 (5.4%) 68 (8.7%) 0.003
Diabetesd, n (%) 93.1 (22.3%) 188 (31.1%) <0.001 375 (24.0%) 204 (25.8%) 0.334
Systolic blood pressure, mmHg 142.9 ± 20.5 141.6 ± 23.7 0.188 143.4 ± 20.9 140.9 ± 22.1 0.006
Use of cardiovascular medicatione, n (%)
 Antithrombotic agents 1713 (97.9%) 584 (96.5%) 0.063 1529 (97.8%) 768 (97.1%) 0.322
 Blood pressure lowering drugs 1729 (98.8%) 591 (97.7%) 0.051 1537 (98.3%) 783 (99.0%) 0.176
 Statins 1553 (88.7%) 513 (84.8%) 0.011 1399 (89.5%) 667 (84.3%) <0.001
High-sensitivity C-reactive protein, mg/L 1.42 (0.71-3.15) 3.33 (1.27-6.91) <0.001 1.01 (0.61-1.72) 5.66 (4.04-8.83) <0.001
Serum creatininef, mg/dl 0.96 ± 0.18 1.54 ± 0.61 <0.001 1.05 ± 0.33 1.22 ± 0.56 <0.001
Serum cystatin C, mg/L 0.89 ± 0.13 1.41 ± 0.42 <0.001 0.96 ± 0.24 1.15 ± 0.42 <0.001
  1. Data are presented as median (interquartile range), mean (± SD) or number (percentage of the total)
  2. aDefined as higher vocational education, college or university
  3. bBody mass index was calculated as weight in kilograms divided by height in meters squared
  4. cDefined as ≥3 Metabolic Equivalent Tasks (MET) during >5 days/week
  5. dDiabetes was considered to be present if a patient reported having received the diagnosis from a physician, was taking antidiabetic drugs, or had an elevated plasma glucose level (≥126 mg/dl in the case of patients who had fasted more than 4 h or ≥200 mg/dl in the case of non-fasting patients)
  6. eAntithrombotic agents ATC code B01. Blood pressure lowering drugs: ATC codes C02, C03, C07, C08 and C09. Statins: ATC code C10AA
  7. fTo convert the values for creatinine to μmol/L, multiply by 88.40
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