| NO-SGAa | SGAa | p value |
---|---|---|---|
N (%) or | N (%) or | ||
Mean (SD) | Mean (SD) | ||
Gender | Â | Â | Â |
 Female | 119 (69.2) | 41(55.4) | 0.037 |
 Male | 53 (30.8) | 33 (44.6) |  |
Years of education in years (SD) | 15.4 (2.9) | 15.2 (3.2) | 0.63 |
Age in years (SD) | 40.3 (12.9) | 40 (11.3) | 0.83 |
Time since diagnosis in years (SD) | 14.3 (11.7) | 13.9 (10.7) | 0.75 |
Previous hospitalizations | 113 (65.7) | 58 (78.4) | 0.047 |
Medications | |||
 Benzodiazepines | 28 (16.3) | 26 (35.1) | 0.001 |
 Antidepressants | 48 (27.9) | 37 (50.0) | 0.0008 |
 Chlorpromazine equivalents | NA | 210 (787) |  |
Mood symptoms | |||
 HAMDb | 8.9 (6.6) | 8.2 (6) | 0.43 |
 YMRSc | 3.1 (4.1) | 3.2 (3.8) | 0.85 |
Diagnosis | |||
 Bipolar I | 115 (66.9) | 63 (85.1) | 0.014 |
 Bipolar II with recurrent depression | 34 (19.7) | 5 (6.8) |  |
 Bipolar NOSd | 18 (10.5) | 3 (4.0) |  |
 Schizoaffective, Bipolar | 5 (2.9) | 3 (4.0) |  |
COMT rs5993883 | |||
 GG | 44 (25.6) | 14 (18.9) | 0.5 |
 GT | 88 (51.2) | 40 (54.1) |  |
 TT | 40 (23.2) | 20 (27.0) |  |
Neuropsychological Tests (SD) | |||
 Rey Visual Memory Immediate Recall | 21.1 (6.8) | 19.1 (6.3) | 0.02 |
 Rey Visual Memory Delayed Recall | 21.2 (6.5) | 19.3 (7.03) | 0.043 |
 CVLT-IIe Trials 1–5 Score (Learning) | 53.9 (11.1) | 48.7 (11.4) | 0.0009 |
 CVLT-II Short Delay Recall Score | 11.4 (3.4) | 10.7 (3.7) | 0.18 |
 CVLT-II Long Delay Recall Score | 12.1 (3.5) | 10.5 (3.7) | 0.0008 |
 WCST-f Total Errors | 23.2 (21.7) | 24.5 (22.3) | 0.67 |
 WCST- Perseverative Responses (Percentile) | 50 (28.9) | 49.9 (31) | 0.95 |
 WCST-Categories | 5.2 (1.7) | 5.1 (1.8) | 0.53 |
 TMTg A Time (seconds) | 29.6 (10.7) | 31.2 (11.6) | 0.28 |
 TMT B Time (seconds) | 71.5 (29.7) | 80.8 (34.9) | 0.03 |
 PGNGh Response Time (Level 1) | 463.5 (50.8) | 467.9 (56.5) | 0.5 |
 PGNG Target Accuracy (Level 1) | 0.9 (0.1) | 0.9 (0.1) | 0.10 |