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Table 1 rTMS parameters in the N = 40 RCTs included in the current meta-analysis

From: Short-term efficacy of repetitive transcranial magnetic stimulation (rTMS) in depression- reanalysis of data from meta-analyses up to 2010

Study (by year and first author); country DLPFC location Definition of location Frequency (Hz) Motor threshold (%) Coil type Coil diameter (mm) Coil angle sham (°) Stimuli/session Trains/session Inter-train interval (s) Sessions Stimulator (company)
George et al. ([1997]); USAa L 5 cm 20 80 F8 45 800 58 10 Cadwell
Avery et al. ([1999]); USA L 5 cm 10 80 45 20 55 10 Cadwell
Kimbrell et al. ([1999]); USAa L 5 cm 20 80 F8 45 800 20 60 10 Cadwell
L 1
Klein et al. ([1999]); Israel R 6 cm 1 110 C 90 90 120 180 10 Cadwell
Loo et al. ([1999]); Australia L 5 cm 10 110 F8 70 45 30 30 10 MagStim
Padberg et al. ([1999]); Germany L 5 cm 10 90 F8 70 90 250 5 30 5 MagStim
L .3 10
Berman et al. ([2000]); USA L 5 cm 20 80 F8 45 20 58 10 Cadwell
Eschweiler et al. ([2000]); Germanya,b L 5 cm 10 90 F8 70 90 20 50 5 MagStim
George et al. ([2000]); USAc L 5 cm 12* 100 F8 45 1600 25* 10 Cadwell
Garcia-Toro et al. ([2001a]); Spain L 5 cm 20 90 F8 90 30 30* 10 MagPro
Garcia-Toro et al. ([2001b]); Spain L 5 cm 20 90 F8 85 90 1200 30 30* 10 MagPro
Manes et al. ([2001]) ; USA L MRI 20 80 F8 TI 20 60 5 MagStim
Boutros et al. ([2002]); USA L 5 cm 20 80 F8 70 90 800 20 58 10 MagStim
Padberg et al. ([2002]); Germanyd L 5 cm 10 100 F8 70 90 1500 15 30 10 MagStim
Fitzgerald et al. ([2003]); Australia L 5 cm 10 100 F8 70 45 1000 20 25 10 MagStim
R 1 300 5 60
Höppner et al. ([2003]); Germanye L 5 cm 20 90 F8 90 20 60 10 MagLite
Loo et al. ([2003]); Australia B 5 cm 15 90 F8 70 TI 24 25 15 MagStim
Nahas et al. ([2003]); USA L 5 cm 5 110 F8 45 1600 22 10 Neotonus
Buchholtz et al. ([2004]); Denmark L 5 cm 10 90 F8 70 90 20 60 15 MagStim
Hausmann et al. ([2004]); Austriaf BS MRI 11* 110* F8 TI 2300* 10 10 10 MagStim
Holtzheimer et al. ([2004]); USA L 5 cm 10 110 F8 45 1600 32 45* 10 MagPro
Kauffmann et al. ([2004]); USA R 5 cm 1 110 C 90 45 120 2 180 10 MagLite
Koerselman et al. ([2004]); Netherlands L 5 cm 20 80 C 60 45 20 30 10 MagPro
Mosimann et al. ([2004]); Switzerland L 5 cm 20 100 F8 90 1600 40 28 10 MagStim
Poulet et al. ([2004]); France L 5 cm 10 80 F8 70 45 20 58 10 MagStim
Rossini et al. ([2005]); Italy L 5 cm 15 100 F8 70 90 900 30 28 10 MagStim
Rumi et al. ([2005]); Brazil L 5 cm 5 120 F8 TS 1250 25 20 20 MagPro
Su et al. ([2005]); Taiwanc L 5 cm 12* 100 F8 70 90 40 10 MagStim
Avery et al. ([2006]); USA L MRI 10 110 F8 70 90 1600 32 28* 15 MagPro
Fitzgerald et al. ([2006]); Australia BS 5 cm 6* 105* F8 70 45 18 28* 10 MagPro
Garcia-Toro et al. ([2006]); Spaing BS 5 cm 11* 110 F8 85 45 60 20* 10 MagPro
Januel et al. ([2006]); France R 5 cm 1 90 F8 TS 2 180 16 MagStim
Anderson et al. ([2007]); UK L 5 cm 10 110 F8 TS 1000 20 30 12 MagStim
Bortolomasi et al. ([2007]); Italy L 5 cm 20 90 C 90 90 800 20 60 5 MagStim
Herwig et al. ([2007]); Germany/Austriah L F3 10 110 F8 70 45 2000 100 8 15 MagStim/Pro
Loo et al. ([2007]); Australiai L 5 cm 10 110 F8 70 TI 30 25 20 MagStim
O’Reardon et al. ([2007]); USA, Australia, Canada L 5 cm 10 120 TS 3000 26 20 Neuronetics
Stern et al. ([2007]); USA L 5 cm 10 110 F8 90 20 52 10 MagStim/MagPro
L 1 1
R 1 1
Bretlau et al. ([2008]); Denmark L 5 cm 8 90 F8 70 TS 1289 20 52 15 MagStim
Mogg et al. ([2008]); UK L 5 cm 10 110 F8 TS 1000 20 55 10 MagStim
  1. Notes: *Mean values. Sham was always administered at the same DLPFC location (left or right or bilateral) as the active rTMS (for the definition of DLPFC location, ’5 cm’ refers to 5 cm rostral (anterior) to sagittal (parasagittal) plane). aIf cross-over design was used then the results of only the parallel double-blind stimulation are included in the current analysis. bThe combined scores of two active rTMS groups (group 1 and 3) are included in the current analysis. cThe combined scores of two HFL rTMS groups (5 Hz and 20 Hz) are included in the current analysis. dSince sham was administered at 100% MT, only the active rTMS with 100% MT group is included in the current analysis. eSince sham was administered to the left DLPFC, only the HFL rTMS group is included in the current analysis. fThe ’active rTMS’ group consists of group A1 (HFL rTMS followed by right-sham) and group A2 (HFL rTMS followed by LFR rTMS). Sham was applied bilaterally (left then right DLPFC). g"Active TMS" group is included in the current analysis (active TMS after single photon emission computed tomography, SPECT, is excluded because patients in this group received rTMS at individualised sites based on the results of SPECT). hSham was administered 5 cm lateral to the F3 location, above the left temporal muscle. iIn contrast to all other studies that utilised a single rTMS (or sham) session/day, rTMS was applied twice/day for 2 weeks, 5 days/week (thus a total of 20 sessions). Abbreviations: B, bilateral DLPFC; BS, bilateral sequential (left then right DLPFC); C, circular; DLPFC, dorsolateral prefrontal cortex; F3, the F3 location of the 10-20 electroencephalogram (EEG) system; F8, figure-of-eight shape; L, left DLPFC; MRI, magnetic resonance imaging; R, right DLPFC; RCT, randomised-controlled trial; rTMS, repetitive transcranial magnetic stimulation; TI, tangential with inactive coil; TS, tangential with sham coil containing embedded magnetic shield.