Skip to main content

Table 2 Areas under ROC curves for MCI and AD groups relative to healthy controls

From: Clinical utility of the cogstate brief battery in identifying cognitive impairment in mild cognitive impairment and Alzheimer’s disease

Composite Clinical group Sensitivity (95% CI) score < 90 Specificity (95% CI) score < 90 Area under ROC curve (95% CIs) Standard error p
Psychomotor/attention AD 52.9% (38.5%, 67.1%) 85.7% (82.8%, 88.3%) 0.73 (0.64, 0.82) 0.05 < 0.0001
  MCI 41.1% (31.7%, 51.1%) 85.7% (82.8%, 88.3%) 0.67 (0.61, 0.73) 0.03 < 0.0001
   Score < 90 Score < 90    
Learning/working memory AD 100.0% (91.5%, 100.0%) 84.7% (81.7%, 87.4%) 0.99 (0.98, 1.00) 0.01 < 0.0001
  MCI 80.4% (71.6%, 87.4%) 84.7% (81.7%, 87.4%) 0.91 (0.87, 0.94) 0.02 < 0.0001
  1. Note: ROC = receiver operating characteristic; MCI = mild cognitive impairment; AD = Alzheimer’s disease; Attention/psychomotor composite = average of the standardized Detection and Identification scores; Learning/working memory composite = average of the standardized One Card Learning and One Back scores; MMSE = Mini Mental State Examination.