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Table 3 Risk factors for suicide ideation in patients with advanced breast cancer patients: Results from univariate and multivariable Logistics regression

From: Suicidal ideation in Chinese patients with advanced breast cancer: a multi-center mediation model study

Variables

Univariate analysis

p

Multivariable analysis

p

Estimates (95% CI)

Estimates (95% CI)

ECOG

1.353 (1.003–1.824)

0.048*

1.133 (0.738–1.740)

0.567

Cancer Stage

0.550 (0.361–0.839)

0.006**

0.508 (0.293–0.880)

0.016*

Emotional distress (HADS)

1.187 (1.143–1.233)

<0.001***

1.090 (1.030–1.153)

0.003**

Insomnia severity (ISI)

1.093 (1.058–1.130)

<0.001***

0.907 (0.921–1.021)

0.246

Depression from PHQ-9

1.361 (1.279–1.448)

<0.001***

1.355 (1.227–1.497)

<0.001***

Health status (EQ-5D-5 L value)

0.096 (0.041–0.228)

<0.001***

1.696 (0.378-7.600)

0.490

Health status (EQ-5D-5 L VAS)

0.972 (0.962–0.982)

<0.001***

1.005 (0.989–1.021)

0.556

MDASI-pain

1.230 (1.136–1.333)

<0.001***

1.116 (0.980–1.272)

0.099

MDASI-fatigue

1.236 (1.142–1.337)

<0.001***

0.899 (0.778–1.038)

0.147

MDASI-upset

1.249 (1.151–1.356)

<0.001***

0.874 (0.760–1.004)

0.058

MDASI-forgetfulness

1.224 (1.125–1.332)

<0.001***

1.159 (1.028–1.306)

0.016*

  1. Abbreviations: ECOG- Eastern Cooperative Oncology Group performance status scale.
  2. Variables entered in the models: cancer stages, ECOG, HADS, PHQ-9, ISI, EQ-5D-5 L value and VAS, MDASI-pain, MDASI-fatigue, MDASI-upset, MDASI-forgetfulness.
  3. ***p<0.001; **p<0.01, *p<0.05.